CHILD-BRIGHT GRIP (Genome-wide sequencing Readiness and Implementation in Practice) Study: a hybrid implementation-effectiveness observational study of clinical genome-wide sequencing in Ontario

Contact

Erin Hsue: erin.hsue@sickkids.ca

Principal Investigators

Robin Hayeems (SickKids, University of Toronto)
Michael Mackley (SickKids, University of Toronto)

Project summary

Genome-wide sequencing is increasingly available as part of the diagnostic work-up for many major brain-based developmental disabilities and other genetic conditions. Access to this test, however, can be limited. This research project is designed to continue to evaluate and advance Genome-wide sequencing Ontario (GSO)—a multi-institutional service developed to deliver GWS to patients across Ontario—and inform its implementation amongst clinicians in specialties outside of medical genetics. This will enable earlier access to GWS for more patients and build capacity in genomic medicine among non-genetics specialists. Moreover, findings will support other provinces in their ongoing efforts to mobilize local access to GWS for their patients.

Research theme: BRIGHT Realities – Projects to effectively bring interventions into the lives of children and their families

Audience: Children and youth with brain-based developmental disabilities in Ontario

Project updates

2023-24

The CHILD-BRIGHT GRIP project has received research ethics approval at its study site. The team has started data collection and analysis and is now identifying barriers and facilitators to develop an implementation strategy.

Follow our work

Members on social media: @RobinHayeems | @MichaelMackley