Enhancing Brain Repair with Metformin (Metformin in CP)


Daniel Warner

Children with cerebral palsy who were born premature face a lifetime of motor impairments, some of which can be treated with physiotherapy. Recent findings suggest that the drug metformin could help motor recovery by recruiting stem cells in the brain to help repair injury. Here, we will evaluate whether metformin combined with physiotherapy enhances motor and thinking skills in children with cerebral palsy.

Research theme:
BRIGHT Beginnings: Projects to optimize brain and developmental outcomes

Age range: 
5­–12 years

Start date:
June 2016

Principal Investigators: 
Dr. Donald J. Mabbott, SickKids
Dr. Darcy Fehlings, Holland Bloorview Kids Rehabilitation Hospital

External links:
Visit the CP Discovery Lab

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