MATernal hyperoxygenation in Congenital Heart Disease (MATCH)


Liqun Sun

Fetuses with congenital heart disease have slower brain development than those without heart disease. This is associated with reduced oxygen delivery to the developing brain. Supplementary inhaled oxygen during the third trimester could be a safe and feasible method of improving oxygenation of the fetal brain. In this study, we will evaluate whether supplementing mothers with oxygen helps brain development in fetuses with congenital heart disease.  

Research theme:
BRIGHT Beginnings: Projects to optimize brain and developmental outcomes

Age range: 
20 weeks gestational age–18 months

Start date:
April 2017

Principal Investigators: 
Dr. Mike Seed, SickKids
Dr. Steven Miller, SickKids

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